Abstract

An ethnomedicinal plant, Pterolobium hexapetalum (Roth) Santapau & Wag (Leguminosae) was analyzed for antimicrobial activity. Bioassay of antimicrobial activity of hexane, chloroform and ethanol leaf extract showed significant activity against the human pathogens such as Proteus vulgaris, Pseudomonas aeruginosa causing urinary tract infections and septicaemia, Salmonella typhi causing typhoid fever, Vibrio species causing diarrheal infections and the fungus Candida albicans. The antimicrobial activity expressed the concentration-dependent against all the tested microorganisms.  Ethanol extracts exhibited the highest antimicrobial activity. The present findings provide an authentic scientific evidence for the traditional usages by various tribes in India. The bioactive compounds responsible for these antimicrobial activities against the tested microorganisms should be isolated and identified to develop a new lead of therapeutic interest.

A6Preliminary Phytochemical Screening and Antimicrobial activity pdf