Abstract
Objective: To compare the efficacy of Bupivacaine 0.5% with Midazolam & Bupivacaine 0.5% used for supraclavicular approach to brachial plexus block in adult patients postoperatively.
Study Design: Randomized controlled clinical trial.
Place and Duration of Study: Rajah Muthiah Medical College and Hospital, Chidambaram, from April 2015 to August 2016.
Methodology: A randomized controlled clinical trial was conducted on 60 ASA- 1 or 2 adult patients undergoing upper limb surgeries under supraclavicular brachial plexus block. Patients were randomly allocated into 2 groups of 30 each. Patients in group M were administered 27.5 ml of 0.5 % Bupivacaine with 2.5 ml of Midazolam (0.05 mg/kg) and those in group B were administered 27.5 ml of 0.5% Bupivacaine with 2.5 ml of distilled water. Hemodynamic varaiables (heart rate, blood pressure), pain scores and rescue analgesic requirements were recorded for 24 hours postoperatively, and compared using unpaired student’s t- test with significance at p < 0.05. Results: The duration of sensory and motor block was significantly longer in group M compared to group B (p < 0.05). Duration of analgesia was prolonged in group M compared to group B. Hemodynamics did not differ between the groups in the studied period. Conclusion: Bupivacaine (0.5%) in combination with Midazolam (0.05 mg/kg) prolonged the duration of motor and sensory blockade and duration of analgesia of brachial plexus block for upper limb surgery. 2016040212dr.MIDAZOLAM WITH BUPIVACAINE 0.5% IMPROVES ANALGESIA QUALITY IN BRACHIAL PLEXUS BLOCK BY SUPRACLAVICULAR APPROACH IN POSTOPERATIVE PERIOD pdf