Tribal medicine is considered as mother of indigenous systems of ethnomedicine. In the present study ethnomedicinal plant survey was carried out among Irular Tribes who settled in Javadhu hills, which is located in Southern Eastern Ghats of Tamil Nadu. About 30 species of ethnoherbal medicinal plants belonging to 13 families were reported in the present study. The survey indicates that many number of ethnomedicinal plants were traditionally used by the Irular tribes of Javadhu hill for the treatment of various diseases.