Plants have been used as medicine throughout the world, more than five hundred and still to occupy an important place in traditional as well as modern system of medicine. Thousand plants have been used in Indian system of medicines.Most of drug obtained from wild plants.Kuttalam taluk,Kadamangudi is situated in the bank of river Nandalaru a branch of river CaveryNagapattinam district,Tamilnadu.The river belt have rich in various medicinal plants.Frequent field survey were undertaken during October 2009 to October 2010.About 242 species have been identified from the study area of these all plants are medicinal value in various ailments to cure for remedial treatments. Among the survey, the family Solanaceae having ten rare and indigenous plants